Penentuan Formula Optimum Body Scrub Berbasis Serbuk Habbatussauda (Nigella sativa L.): Karakterisasi Fisik dan Uji Antioksidan
DOI:
https://doi.org/10.54082/jupin.2650Kata Kunci:
antioksidan, body scrub, DPPH, Habbatussauda, Nigella sativa L.Abstrak
Body scrub merupakan sediaan kosmetik untuk membantu eksfoliasi kulit melalui pengangkatan sel-sel kulit mati sehingga menjaga kebersihan dan kesehatan kulit. Habbatussauda (Nigella sativa L.) merupakan tanaman herbal kaya senyawa bioaktif seperti thymoquinone, flavonoid, senyawa fenolik, vitamin, mineral, dan asam lemak esensial yang berpotensi sebagai antioksidan alami. Penelitian ini bertujuan mengembangkan body scrub berbahan serbuk habbatussauda, mengevaluasi karakteristik fisiknya, serta mengkaji aktivitas antioksidan secara eksperimental menggunakan empat formula, yaitu F0 sebagai kontrol tanpa serbuk habbatussauda, F1 berkonsentrasi 5%, F2 sebesar 10%, dan F3 sebesar 15%. Parameter evaluasi meliputi organoleptik, homogenitas, pH, daya sebar, serta aktivitas antioksidan menggunakan metode 2,2-diphenyl-1-picrylhydrazyl (DPPH) dengan vitamin C sebagai kontrol positif untuk menentukan potensi antioksidan setiap formula yang dihasilkan secara optimal. Hasil penelitian menunjukkan bahwa seluruh formula menghasilkan sediaan yang homogen dengan nilai pH berkisar antara 5-6 sehingga sesuai dengan pH fisiologis kulit. Peningkatan konsentrasi serbuk Habbatussauda menyebabkan warna sediaan semakin pekat, konsistensi meningkat, dan daya sebar cenderung menurun. Formula 1 dan Formula 2 memenuhi persyaratan daya sebar, sedangkan Formula 3 memiliki daya sebar di bawah standar. Pengujian aktivitas antioksidan menunjukkan nilai IC₅₀ Formula 1, Formula 2, dan Formula 3 berturut-turut sebesar 5,39 ppm, 4,97 ppm, dan 4,45 ppm, yang termasuk kategori aktivitas antioksidan sangat kuat. Meskipun Formula 3 memiliki aktivitas antioksidan tertinggi, Formula 2 ditetapkan sebagai formula optimum karena memberikan keseimbangan terbaik antara karakterisasi fisik yang memenuhi persyaratan dan aktivitas antioksidan yang sangat kuat. Temuan ini menunjukkan bahwa body scrub berbasis serbuk Habbatussauda berpotensi dikembangkan sebagai sediaan eksfoliasi alami yang juga memberikan manfaat antioksidan.
Referensi
Agata, S. D., & Jayadi, L. (2022). Formulasi Lulur Body Scrub Beras Ketan Hitam (Oryza sativa var. glutinosa) Dengan Perpaduan Yogurt Sebagai Zat Aktif. Jurnal Riset Kefarmasian Indonesia, 4(3), 332–352. https://doi.org/10.33759/jrki.v4i3.293
Akanny, E., & Kohlmann, C. (2024). Predicting tactile sensory attributes of personal care emulsions based on instrumental characterizations: A review. International Journal of Cosmetic Science, 46(6), 1035–1063. https://doi.org/10.1111/ics.13004
Aslani, M. R., Saadat, S., & Boskabady, M. H. (2024). Comprehensive and updated review on anti-oxidant effects of i>Nigella sativa/i> and its constituent, thymoquinone, in various disorders. Iranian Journal of Basic Medical Sciences, 27(8). https://doi.org/10.22038/ijbms.2024.75985.16453
Bagas Am Trianloka, Lutfi Chabib, Widya H P Maharani, Annisa Fitria, Arba P Ramadani, Arman Suryani, & Ferdy Firmansyah. (2025). Enhancing Hair Follicle Stimulation: A Nanoliposome-Based Delivery of Lavender Essential Oil (Lavandula angustifolia Mill.). Tropical Journal of Natural Product Research, 9(8). https://doi.org/10.26538/tjnpr/v9i8.27
Boggula, N., Gari, M. R. N. R., Kallu, C., & Vallakati, N. (2025). Assessment of Antioxidant Activity of Nigella sativa seed: An In Vitro Approach. Asian Journal of Pharmaceutical Research and Development, 13(4), 47–51. https://doi.org/10.22270/ajprd.v13i4.1591
Chabib, L., Ar Rodli, F. H., Nugroho, B. H., Suryani, A., & Firmansyah, F. (2024). Development of nanoliposome formulation of beta-carotene using high speed homogeniser method. Pharmacy Education, 24(2), 1–8. https://doi.org/10.46542/pe.2024.242.18
Chabib, L., Hartanto, Syukri, Y., & Suryani, A. (2024). Cashew leaf extract gel as antibacterial with CMC-Na as gelling agent. 020018. https://doi.org/10.1063/5.0205318
Chabib, L., Suryani, A., Dewi, L. S., Noviani, H., Maharani, W. H. P., & Indraswari, A. A. (2023). Pineapple fruit extract (Ananas comosus L. Merr) as an antioxidant and anti-acne agent made with the nano-emulsion gel delivery system. Pharmacy Education, 23(2), 126–132. https://doi.org/10.46542/pe.2023.232.126132
Chabib, L., Suryani, A., Munawiroh, S. Z., Mariyam, S., Nafiah, Z., & Laksitorini, M. D. (2024). Enhancing the Physical Characteristics and Shelf Life of Rice Water (Oryza sativa L.) Gel Shampoo: The Role of Propylene Glycol Concentration. International Journal of Applied Pharmaceutics, 364–370. https://doi.org/10.22159/ijap.2024v16i2.49766
Chabib, L., Suryani, A., Noviani, H., & Werdyani, S. (2024). Biosynthesis of gold nanoparticles from pineapple bromelain isolate as antioxidant. 020019. https://doi.org/10.1063/5.0205319
Dallay, C., Malhiac, C., Picard, C., & Savary, G. (2024). Fragrance in dermocosmetic emulsions: From microstructure to skin application. International Journal of Cosmetic Science, 46(1), 1–23. https://doi.org/10.1111/ics.12896
Ervina, A., Santoso, J., Prasetyo, B. F., Setyaningsih, I., & Tarman, K. (2020). Formulation and characterization of body scrub using marine alga Halimeda macroloba, chitosan and konjac flour. IOP Conference Series: Earth and Environmental Science, 414(1), 012004. https://doi.org/10.1088/1755-1315/414/1/012004
Evanti, A., Wargasetia, T., & Gunadi, J. (2025). Role of Nigella sativa L. seed (black cumin) in preventing photoaging (Review). Biomedical Reports, 23(2), 1–13. https://doi.org/10.3892/br.2025.2009
Green, M., Kashetsky, N., Feschuk, A., & Maibach, H. I. (2022). Transepidermal Water Loss (TEWL): Environment and Pollution-A Systematic Review. Skin Health and Disease, 2(2), ski2.104. https://doi.org/10.1002/ski2.104
Gulcin, İ. (2025). Antioxidants: A comprehensive review. Archives of Toxicology, 99(5), 1893–1997. https://doi.org/10.1007/s00204-025-03997-2
Gulcin, İ., & Alwasel, S. H. (2023). DPPH Radical Scavenging Assay. Processes, 11(8), 2248. https://doi.org/10.3390/pr11082248
Purwandari, V., Silitonga, M., Thaib, C. M., & Sitohang, I. K. (2018). Formulasi Sediaan Krim Lulur Kopi Arabika (Coffea arabica) Sebagai Anti-Aging. Jurnal Farmanesia, 5(1), 50–63. https://doi.org/10.51544/jf.v5i1.2728
Rina Wijayanti, Sabrina M Putri, Rissa L Vifta, Windi Susmayanti, Arman Suryani, & Naniek Widyaningrum. (2026). Tyrosinase Inhibitory and Antioxidant Effects: Water Fraction from Parijoto (Medinilla speciosa Blume) Fruit as a Potential Natural Therapeutic Agent. Tropical Journal of Natural Product Research, 10(7). https://doi.org/10.26538/tjnpr/v10i7.1
Safitri, M., Aprilliani, A., Zaky, M., & Azkiya, S. M. (2024). Formulation And Physical Evaluation of Body Scrub Cream From 95% Ethanol Extract of Breadfruit Peel (Artocarpus altilis) as Antioxidants. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 11(3), 335–344. https://doi.org/10.20473/jfiki.v11i32024.335-344
Sari, D. E. M., Fitrianingsih, S., & Zulkarya, L. G. (2024). Variations In Concentration Of Tween 80 And Span 80 Emulgator In Body Scrub Extract Formulation Watermelon (Citrullus lanatus) Water On Physical And Chemical Stability. Proceeding Cendekia International Conference Health and Technology, 2(2024), 311–321. https://doi.org/https://proceedings.centamaku.ac.id/article/view/138
Suryani, A., Affani, A. R., Safitri, B. W., Azis, I. A., Aldo, M. F., & Sofia, H. (2025). Innovative Formulation of Solid Lipid Nanoparticle Loaded with Carrot Seed Essential Oil for Potential Antioxidant Activity and Sun Protection. Tropical Journal of Natural Product Research, 9(12), 6239–6248. https://doi.org/10.26538/tjnpr/v9i12.43
Suryani, A., & Cahyaningsih, T. (2025). Optimasi Formulasi Cleansing Balm Minyak Biji Tomat (Solanum lycopersicum) dengan Simplex Lattice Design: Karakteristik Fisik dan Efek Anti-Aging. Journal of Pharmaceutical and Sciences, 391–401. https://doi.org/10.36490/journal-jps.com.v8i1.561
Suryani, A., Chabib, L., Fitria, A., Nurlina, S., & Kartika, E. R. (2025). Peppermint essential oil nanoliposomes: Innovative formulation for effective hair growth. Journal of Applied Pharmaceutical Science, 15(6), 178–189. https://doi.org/10.7324/JAPS.2025.207281
Suryani, A., Shafira Istiqhfarin, H. A., Hidayah, N., Nitisara, N. N., Aryanti, A. M., Ardana, R., & Kartika, E. R. (2025). Synergistic modification of polyvinyl alcohol and natural phospholipids: Nanoliposomal carrier for Sonneratia caseolaris L. delivery and therapeutic care. Journal of Applied Pharmaceutical Science, 15(12), 251–265. https://doi.org/10.7324/JAPS.2025.243159
Suryani, A., & Wahyuni, T. (2025). Formulasi Hand &Body Lotion dengan Minyak Biji Tomat (Solanum lycopersicum L.): Studi InovatifPelembab danAntioksidan untuk Perawatan Kulit. Indonesian Journal of Medical and Pharmaceutical Science, 4(1), 60–70. https://doi.org/10.30659/ijmps.v4i1.370
Widyasanti, A., & Azara, W. N. (2024). Formulasi Body Scrub dengan VCO (Virgin Coconut Oil) dan Serbuk Daun Jeruk Purut (Citrus hystrix). Jurnal Teknologi Agro-Industri, 11(2), 104–111. https://doi.org/10.34128/jtai.v11i2.200.
Yoga Wardana, F., Islamiyah, T. N., & Arifin, I. P. (2025). Antioxidant Activity and Body Scrub Formulation from Yellow Dragon Fruit Peel (Selenicereus megalanthus) Extract. Borneo Journal of Pharmascientech, 9(1), 21–28. https://doi.org/10.59053/bjp.v9i1.542
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Hak Cipta (c) 2026 Arman Suryani, Hilmalia Indriyani, Risnainda Ramadhaningtias , Indah Rahmawati , Ina Liana, Icha Vanska Amalia , Iga Putris Ayuning Tyas , Iche Rahma Saputri
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